Silica gel column chromatography was used for the isolation and purification of the chemical constituents of the pericarp of Illicium macranthum. Ma, Hai-juan Ma, Chang-hua Huang, Jian-mei Conclusions: In vivo effects of Solanum extracts were demonstrated, suggesting that this genus could be further explored as a new antileishmanial alternative. An increase of IFN-γ ( p 0.05) were observed for IL-12. extract showed the highest efficacy and was superior ( p 0.05) to GTM. All the tested extracts were able to control the infection, compared with the infected and untreated group. Results: Neither death nor loss of weight higher than 10% was observed. Methods: Animals were infected with 5 Ã- 10ⶠmetacyclic promastigotes and 30-day post-infection, a treatment with 30 mg/kg of Solanum extracts or Glucantime ® (GTM) was applied intralesionally every four days to complete 5 doses. amazonensis BALB/c mice model for experimental cutaneous leishmaniasis. In this study, the in vivo efficacy of Solanum spp. Currently, there have been renewed interests worldwide in plants as pharmaceutical agents.
Extracts in an Animal Model of Cutaneous Leishmaniasis.Ĭos, Paul Janssens, Jo Piñón, Abel Cuesta-Rubio, Osmany Yglesias-Rivera, Arianna DÃaz-GarcÃa, Alexis Vilegas, Wagner Monzote, Lianetīackground: Leishmaniasis is a complex protozoa disease caused by Leishmania genus (Trypanosomatidae family). PMID:25698893Įfficacy of Four Solanum spp. Complete descriptions, distributions and preliminary conservation assessments of all new species are given. (Potato clade) is endemic to Cajamarca Department in Peru, and is most similar to the widespread Solanum caripense Dunal. (Morelloid clade) is found in low elevation habitats on the eastern Andean slopes and in Amazonia of Peru and Bolivia and is most similar to the higher elevation species Solanum aloysiifolium Dunal of Bolivia and Argentina. Solanum arenicola Särkinen & P.Gonzáles, sp. (Morelloid clade) is found on the eastern Andean slopes in Ecuador, Peru and Bolivia and is most similar to the widespread lower elevation species Solanum polytrichostylum Bitter. Solanum antisuyo Särkinen & S.Knapp, sp.
(Morelloid clade) is widespread from Ecuador to Bolivia and is most similar to Solanum macrotonum Dunal from Central and northern South America. Solanum longifilamentum Särkinen & P.Gonzáles, sp. Särkinen, Tiina Gonzáles, Paúl Knapp, SandraĪbstract Four new species of “non-spiny†Solanum from South America are described. Four new non-spiny Solanum (Solanaceae) species from South America